Skip to Content

The Risks of Self-Medicating with Alcohol

People have used alcohol to relieve pain since ancient times. Laboratory studies confirm that alcohol does indeed reduce pain in humans and in animals. Moreover, recent research suggests that as many as 28 percent of people experiencing chronic pain turn to alcohol to alleviate their suffering. Despite this, using alcohol to alleviate pain places people at risk for a number of harmful health consequences.

What are the risks?

Mixing alcohol and pain medicines can be harmful.

  • Mixing alcohol and acetaminophen can cause acute liver failure
  •  Mixing alcohol and aspirin increases risk for gastric bleeding
  •  Alcohol increases analgesic, reinforcing, and sedative effects of opiates, elevating risk for combined misuse of alcohol and opiates as well as overdose.

If you’re taking medications to manage your pain, talk to your doctor or pharmacist about any reactions that may result from mixing them with alcohol.

Analgesic doses of alcohol exceed moderate drinking guidelines.

  • The greatest pain-reducing effects occur when alcohol is administered at doses exceeding guidelines for moderate daily alcohol use.*
  • Tolerance develops to alcohol’s analgesic effects so that it takes more alcohol to produce the same effects. Increasing alcohol use to stay ahead of tolerance can lead to other problems, including the development of alcohol dependence.

*According to the Dietary Guidelines for Americans, drinking in moderation is defined as having no more than 1 drink per day for women and no more than 2 drinks per day for men.

Chronic alcohol drinking makes pain worse.

  • Withdrawal from chronic alcohol use often increases pain sensitivity which could motivate some people to continue drinking or even increase their drinking to reverse withdrawal-related increases in pain.
  • Prolonged, excessive alcohol exposure generates a painful small fiber peripheral neuropathy, the most common neurologic complication associated with alcoholism.

If you use alcohol to relieve your pain, it is important to learn about possible adverse health effects. Ask your health care provider if any alcohol use is safe for you.


1. USDA/DHHS. Dietary Guidelines for Americans. Chapter 9–Alcoholic Beverages. Washington, DC: US Government Printing Office; 2005, p. 43–46.

2. Brennan P.L., Schutte K.K., Moos R.H. (2005) Pain and use of alcohol to manage pain: prevalence and 3-year outcomes among older problem and non-problem drinkers. Addiction 100:777–786.

3. Riley III JL, King C. (2009) Self-report of alcohol use for pain in a multi-ethnic community sample. J Pain10:944–952.


comments powered by Disqus

Related Articles